CD82 anticorps

N° du produit ABIN1106584

Cet anticorps Souris Monoclonal détecte spécifiquement CD82 dans WB, FACS, IHC (p), IP, IF et Func. Il présente une réactivité envers Humain et a été mentionné dans 7+ publications.

Aperçu rapide pour CD82 anticorps (ABIN1106584)

Antigène: CD82

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD82 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)

Clone: C33

Détail du produit anti-CD82 anticorps

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein-A Affinity Chromatography

Immunogène: C91/PL (Human HTLV-1+ T cell line)

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), approx. pH 7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-CD82 (ABIN1106584)

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." dans: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Dráberová, DAgostino, Caracciolo, Sládková, Sulimenko, Sulimenko, Sobol, Maounis, Tzelepis, Mahera, K?en, Legido, Giordano, Mörk, Hozák, Dráber, Katsetos: "Overexpression and Nucleolar Localization of ?-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma." dans: Journal of neuropathology and experimental neurology, Vol. 74, Issue 7, pp. 723-42, (2015) (PubMed).

Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." dans: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

Coral, Pucillo, Leonardi, Fonsatti, Altomonte, Maio: "Triggering of HLA-DR antigens differentially modulates tumor necrosis factor alpha release by B cells at distinct stage of maturation." dans: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 8, Issue 5, pp. 581-8, (1997) (PubMed).

Ueda, Ichikawa, Tamaru, Mikata, Akakura, Akimoto, Imai, Yoshie, Shiraishi, Yatani, Ito, Shimazaki: "Expression of the KAI1 protein in benign prostatic hyperplasia and prostate cancer." dans: The American journal of pathology, Vol. 149, Issue 5, pp. 1435-40, (1996) (PubMed).

Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

Détails sur CD82

Antigène: CD82

Autre désignation: CD82

Sujet: CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.Synonyms: C33 antigen, IA4, Inducible membrane protein R2, KAI1, Kangai-1, Metastasis suppressor Kangai-1, SAR2, ST6, Suppressor of tumorigenicity protein 6, TSPAN27, Tetraspanin-27

ID gène: 3732

NCBI Accession: NP_001020015

UniProt: P27701

Pathways: Signalisation p53